4 August 2026
New preprint: flexibility in the ESX-5 secretion pore

A new preprint from Christina Ritter, Grzegorz Chojnowski and colleagues at EMBL Hamburg, with Kate as a co-author, is now up on bioRxiv: Intrinsic flexibility of Type VII secretion central pore is required for substrate translocation.
It follows on from earlier work on the ESX-5 pore complex and shows that flexibility in the pore-forming helices of EccC5 is needed for substrates to get through the mycobacterial type VII secretion system.
Read the preprint on bioRxiv.